Mood Disorders

High School Peer-to-Peer Program May Increase Early Depression Detection

March 19, 2018

The researchers found that after implementation of the campaigns, students had improved knowledge and attitudes toward depression, increased confidence in identifying and referring peers with depression, improved help-seeking intentions, and reduced stigma.

Incidence of Breast Cancer Investigated Among Women With Schizophrenia

March 16, 2018

The researchers included 12 cohorts (760 women) in this meta-analysis. Pooled analysis showed that schizophrenia was associated with a significantly increased risk of breast cancer incidence in women (SIR, 1.31; P<0.001).

Does Oseltamivir Use Increase the Risk of Suicide in Pediatric Patients?

By March 13, 2018

To investigate a possible relationship, researchers from the University of Illinois and the Children's Hospital University analyzed 21,407 suicide-related events among 1 to 18 year old individuals.

Teens With Mental Health Conditions More Likely to Receive Opioids Long-Term

March 13, 2018

Teens with pre-existing mental health conditions, tx more likely to transition to long-term opioid use

Latuda Indication Expanded to Treat Pediatric Bipolar Depression

By March 07, 2018

Latuda's (lurasidone HCI; Sunovion) expanded indication has been approved for pediatric patients aged 10 to 17 years who have major depressive episodes associated with bipolar I disorder.

Treatment Shows Promise for Delirium Prevention in Critically Ill

March 05, 2018

The researchers found that nocturnal dexmedetomidine was associated with a greater proportion of patients who remained delirium-free during the ICU stay (relative risk, 0.44; P=0.006).

Progestin-Only Contraceptives and Depression: Is There a Link?

By February 28, 2018

Study quality was graded according to the United States Preventive Services Task Force and the Cochrane Risk of Bias Tools.

Serotonin Syndrome Risk Assessed With Concomitant Triptan, SSRI/SNRI Use

February 27, 2018

Researchers question FDA advisory warning on risk of concomitant use

Can Diet Adherence Help Cut Depression Risk in Adults?

By February 26, 2018

The results showed that those participants who fell into the top group for DASH diet adherence had 11% lower odds of becoming depressed versus those in the lowest group of DASH adherence.

Adolescent Depression Identification, Initial Management Guidelines Updated

February 26, 2018

This updated to guidelines is used to address practice preparation, identification, assessment, and initial management of adolescent depression.

Can Haloperidol Help Survival in Critically Ill Who Are At-Risk of Delirium?

February 22, 2018

There was no statistically significant difference in any of the 15 secondary outcomes, including delirium incidence, delirium-free and coma-free days, and duration of mechanical ventilation, ICU, and hospital length of stay.

Antidepressants Compared and Ranked for Treatment of Major Depressive Disorder

February 22, 2018

Researchers found that in head-to-head studies, the most effective antidepressants were agomelatine, amitriptyline, escitalopram, mirtazapine, paroxetine, venlafaxine, and vortioxetine, while the least efficacious were fluoxetine, fluvoxamine, reboxetine, and trazodone.

Connections Between Depression Severity and HIV Treatment Failure Explored

February 22, 2018

During follow-up, 18.8% of scheduled visits were missed, 21.8% of viral loads were detectable, and the mortality rate was 1.5 deaths for 100 person-years; a dose-response relationship was seen for percentage of days with depression in each outcome.

New Test May Help Diagnose Autism Earlier in Children

By February 20, 2018

In this study, researchers explored the association of proteotoxic damage with autism spectrum disorder.

CDC: Prevalence of Depression Examined Among U.S. Adults

February 14, 2018

Depression more common in women; lower among non-Hispanic Asians than other ethnic groups

Addressing Sensitive Topics With Patients: An Interview With Windel Stracener, MD

By February 14, 2018

"Patients must feel that you are empathetic and do not judge them. This is key not only to discussing weight, but to any subject that comes up," said Dr Windel Stracener, a family practitioner for 22 years.

Depression Treatment Initiation Among Newly Diagnosed 'Suboptimal', Says Study

By February 13, 2018

A total of 241,251 adults with newly diagnosed depression were assessed for this study.

Cognitive Enhancement Therapy May Benefit Adults With Autism

February 13, 2018

Participants treated with CET were significantly more likely to gain competitive employment

Is Cranial Electrical Stimulation Effective for Pain, Depression, Anxiety?

February 13, 2018

In patients with anxiety and depression, low-strength evidence of a possible modest benefit was seen in 4 trials conducted more than 40 years ago and in one recent trial compared with sham treatments.

Prazosin and placebo exhibit similar efficacy in post-traumatic stress disorder: The PACT trial

February 12, 2018

In patients with nocturnal symptoms of post-traumatic stress disorder (PTSD), prazosin did not significantly reduce nightmares or improve quality of sleep compared to placebo at 10 or 26 weeks.

Acne Linked to Significantly Higher Risk of Major Depressive Disorder

February 09, 2018

The researchers found that the probability of developing MDD was 18.5 and 12% among patients with acne and in the general population without acne over the 15-year follow-up period.

Novel Therapy for Major Depressive Disorder Gets Breakthrough Designation

By February 08, 2018

The Breakthrough Therapy designation is intended to offer a potentially expedited development path and review for promising drug candidates.

He Said, She Said: Clinician Sued After Patient Suffers Severe Drug Reaction

By February 07, 2018

It is essential to document warnings, especially significant ones, like this.

To What Extent Can Postnatal Depression Impact Child Behavior?

February 02, 2018

For mothers with moderate, marked, and severe PND, the odds ratios for child behavioral disturbance were 2.22, 1.91, and 2.39, respectively.

NDA for Novel Major Depressive Disorder Treatment Submitted to FDA

By January 31, 2018

The NDA submission is based on a comprehensive clinical efficacy and safety package with data from more than 30 clinical trials.

Are Psychiatric Drugs Being Overprescribed in Children and Adolescents?

By January 30, 2018

"Our results show that, at a population level, prescriptions of stimulants and antidepressant medications for children and adolescents do not appear to be prescribed at rates higher than the known rates for psychiatric conditions they are designed to treat," said the study's lead author, Dr. Ryan Sultan.

Specific White Matter Patterns Linked to Youth Psychopathology

January 29, 2018

The feature most associated with both of these traits was a brain white matter pattern reflecting frontotemporal connectivity and crossing fibers in the uncinate fasciculus.

Written Exposure Therapy Found to Be Effective for PTSD

January 24, 2018

The 24-week assessment showed the largest difference between treatments. The WET group had significantly fewer dropouts than the CPT group (4 versus 25).

Greater Pediatric, Public Health Interaction Needed for Failing Child Care

January 23, 2018

Pediatricians and public health professionals frequently interact to the benefit of children and their families; however, increasing integration of the two disciplines is critical for improving child health.

Significant Links Between Depressive Symptoms and Mortality in CA Patients

January 23, 2018

The researchers found that greater depressive symptoms were associated with significantly shorter survival (hazard ratio, 0.868; P<0.001), higher rates of chemoradiation interruption (odds ratio, 0.865; P=0.010).