Miscellaneous Urogenital Disorders

New Staging System Predicts CKD Progression in Children

April 11, 2018

"CKD staged by level of eGFR and proteinuria characterizes the timeline of progression and can guide management strategies in children," the authors write.

Caffeine Citrate Helps Reduce Acute Kidney Injury in Preemies

April 04, 2018

The researchers found that AKI occurred in 18.1% of neonates in the first seven days after birth and occurred less frequently among neonates who received caffeine versus those who did not (11.2 versus 31.6%; P<0.01).

Trained Navigators Help Patients With Kidney Transplant Process

March 27, 2018

Time from referral to waitlisting was 126 days longer for intervention patients. While there was no difference in waitlisting in the early period between intervention and control patients (hazard ratio, 1.03; 95% confidence interval, 0.69 to 1.53), intervention patients were 3.3 times more likely to be waitlisted after 500 days.

Low Sperm Count Associated With Worse Cardiometabolic Health

March 19, 2018

Low sperm counts linked to hypogonadism, higher BMI, hypertension, dyslipidemia, metabolic syndrome

CDC: Acute Kidney Injury Hospitalization Rates Examined in the U.S.

By March 16, 2018

For the report, AKI was defined as the occurrence of at least 1 diagnostic code 584 (acute renal failure) or the occurrence of at least 1 procedure code of 39.95 (hemodialysis) or 54.98 (peritoneal dialysis).

Balanced crystalloids decreases adverse kidney events compared to saline among critically ill

March 06, 2018

Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury events compared to normal saline among intensive care unit (ICU) patients.

Balanced Crystalloids May Cut Kidney Complications Compared With Saline

By February 28, 2018

The results showed no difference in the number of hospital-free days between either group but the balanced crystalloids group had a lower incidence of major adverse kidney events ≤30 days vs the saline group.

Cognitive Impact of Chronic Kidney Disease in Children, Investigated

February 23, 2018

The mean differences in FSIQ were −10.5 for all CKD stages, −9.39 predialysis, −16.2 for dialysis, and −11.2 for transplant compared with the general population.

Ulipristal Assessed in Symptomatic Uterine Leiomyomas

February 20, 2018

The researchers found that amenorrhea was achieved by 47.2, 58.3, and 1.8% of patients in the ulipristal 5mg and 10mg, and placebo groups, respectively.

Addressing Sensitive Topics With Patients: An Interview With Windel Stracener, MD

By February 14, 2018

"Patients must feel that you are empathetic and do not judge them. This is key not only to discussing weight, but to any subject that comes up," said Dr Windel Stracener, a family practitioner for 22 years.

Statin Use May Protect Against Kidney Stone Formation

By February 09, 2018

For this study, researchers aimed to determine the impact of statin use on the risk of nephrolithiasis and to assess whether higher lipid levels were associated with the risk of stone formation.

Transgender, gender nonconforming youths underutilize health care

February 05, 2018

Nearly twice the number of youths who identify as transgender or gender nonconforming (TGNC) stated their health to be fair, poor, or good as opposed to very good or excellent when compared with youths who identified as cisgender.

Toxic Plant Extract Shows Promise in Early Male Birth Control Studies

February 02, 2018

While the male hormonal birth control pill option is in clinical human trials and likely closer to market, it has several potential side effects: In addition to potentially causing weight gain and changes in libido.

Living kidney donation associated with some increased health risks

January 31, 2018

Living kidney donation was associated with higher diastolic blood pressure, lower estimated glomerular filtration rates, and increased relative risk of preeclampsia and end-stage renal disease (ESRD).

FDA Approves Generic Bumex Tablets

By January 30, 2018

The company stated that they are prepared to begin shipping product to wholesalers in early February 2018.

Kidney Injury Incidence Following Non-Kidney Transplants Common in Children

January 09, 2018

The researchers assessed AKI in the first year after transplant and found that perioperative AKI (within the first week) occurred in 67% of children and that AKI after the first week occurred in 36%.

Emergency-Only Hemodialysis Tied to Higher-Mortality Rates

December 19, 2017

The mean 3-year relative hazard of mortality was increased for patients receiving emergency-only versus standard hemodialysis after adjustment for propensity score (hazard ratio, 4.96; 95% confidence interval, 0.93 to 26.45; P=0.06).

Antiretroviral Combination Linked to Increased CKD Risk

By December 08, 2017

The risk of chronic kidney disease (CKD) may be increased in patients living with HIV receiving tenofovir (TDF) with a ritonavir-boosted protease inhibitor compared to those who receive TDF with a non-nucleosidic reverse transcriptase inhibitor (NNRTI)

Possible New Marker of Kidney Disease Identified in Sickle Cell

December 05, 2017

Subsequently, 18 extracellular proteins were focused on, including CP, a protein involved in iron metabolism.

Does Sodium Bicarbonate Benefit Patients With Impaired Kidney Function Undergoing Angiography?

November 14, 2017

A total of 5,177 patients at high risk for renal complications were randomized and scheduled for angiography to receive intravenous sodium bicarbonate or sodium chloride and 5 days of oral acetylcysteine or placebo.

Sertraline May Not Benefit Non-Dialysis Dependent CKD Patients With MDD

November 07, 2017

The researchers found that there was a change in the 16-item Quick Inventory of Depression Symptomatology-Clinician Rated of −4.1 in the sertraline group and −4.2 in the placebo group.

Tolvaptan Slows Loss of Renal Function in Later-Stage ADPKD

November 06, 2017

Reduction in decline in eGFR for patients with later-stage autosomal dominant polycystic kidney disease

Uric Acid-Lowering Therapy May Improve Renal Outcomes in CKD Patients

By November 03, 2017

Uric acid-lowering therapy might improve kidney outcomes, including kidney failure events, proteinuria, and the rate of change in eGFR, and seem to reduce the risk of cardiovascular events in adults with CKD.

Regular Coffee Consumption May Aid Chronic Kidney Disease Patients

November 03, 2017

Compared with individuals in the first quartile of caffeine consumption, those in the second, third, and fourth quartiles had adjusted hazard ratios for mortality of 0.88.

Nutritional Interventions Could Benefit Chronic Kidney Disease

November 02, 2017

Dietary interventions may be used for conservative uremia management and to delay or prevent dialysis therapy, say the authors of the review.

Nephrologist Follow-Up Frequency Examined Post-Severe AKI

October 16, 2017

Respondents were asked to rank their likelihood of recommending follow-up for each patient after hospital discharge.

Drug Combo Efficacy Examined for Patients with HCV and Kidney Disease

October 12, 2017

"Treatment with glecaprevir and pibrentasvir for 12 weeks resulted in a high rate of sustained virologic response in patients with stage 4 or 5 chronic kidney disease and HCV infection," the authors write.

Sleep Duration, Quality Tied to Chronic Kidney Disease Progression

September 15, 2017

Shorter sleep duration, greater sleep fragmentation linked to greater decline in eGFR

Biomarkers ID'd That May Enhance Prediction of Renal Function Decline

September 11, 2017

The researchers found in an eGFR trajectory analysis that 10.1% of participants were rapid decliners, with a mean decrease of 2.9 mL/min/1.73 m²/year.

Intensive Blood Pressure Control Linked to Increased CKD Risk

September 08, 2017

However, cardiovascular events, all-cause mortality risk decrease with intensive blood pressure lowering