Warfarin vs. Rivaroxaban: Outcomes of Temporary Interruption
the MPR take:
After temporary interruption of anticoagulant therapy, are the outcomes for patients with atrial fibrillation taking warfarin and rivaroxaban similar? Yes, says a study in the journal Circulation. During the at-risk period, patients who were taking warfarin had similar rates of stroke/systemic embolism as those who were taking rivaroxaban (0.3% vs. 0.41%, respectively). The risk of major bleeding was also similar between the two groups. Since temporary interruption of anticoagulant therapy is commonplace, researchers agree that more investigation is needed to determine optimal strategies for managing patients with atrial fibrillation who require a break in therapy.
Background- During long-term anticoagulation in atrial fibrillation, temporary interruptions (TIs) of therapy are common, but the relationship between patient outcomes and TIs has not been well studied. Methods and Results- In the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition ...
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