Stroke History Heightens Adverse Surgical Outcomes Risk
(HealthDay News) — A history of a stroke is associated with worse outcomes following elective surgery, according to a study published in the July 16 issue of the Journal of the American Medical Association.
Mads E. Jørgensen, MB, from the University of Copenhagen in Denmark, and colleagues utilized the Danish nationwide cohort study (2005–2011) which included all patients aged ≥20 years undergoing elective noncardiac surgeries (481,183 surgeries). The authors sought to assess time elapsed between stroke and surgery.
The researchers found that crude incidence rates of major adverse cardiovascular events (MACE) among patients with (7,137) and without (474,046) prior stroke were 54.4 vs. 4.1 per 1,000 patients. The odds ratios (ORs) for MACE were 14.23 for stroke <3 months prior to surgery; 4.85 for stroke 3–<6 months prior; 3.04 for stroke 6–<12 months prior; and 2.47 for stroke ≤12 months prior, compared with patients without stroke. For 30-day mortality, similar patterns were seen. Within the stroke subgroup, risk leveled off after nine months.
"A history of stroke was associated with adverse outcomes following surgery, in particular if time between stroke and surgery was <9 months," the authors write.
Several authors disclosed financial ties to the pharmaceutical industry.