STEMI Outcomes in Seniors Appear Similar With Shorter, Longer Stays
(HealthDay News) — For older patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI), outcomes are similar for discharge after 48 hours vs. four to five days, according to a study published in the March 31 issue of the Journal of the American College of Cardiology.
Rajesh V. Swaminathan, MD, from Weill Cornell Medical College in New York City, and colleagues examined whether shorter length of stay (LOS) is safe for older patients undergoing PCI for STEMI. Data were collected for 33,920 patients with STEM who were ≥65 years of age and treated with primary PCI from 2004–2009. Overall, 26.9, 46.3, and 26.8% of patients had short (no more than three days), medium (four to five days), and long (more than five days) LOS, respectively.
The researchers found that for medium vs. short LOS there were no significant differences in 30-day all-cause mortality (hazard ratio [HR], 1.00; 95% confidence interval [CI], 0.74–1.34) or in major adverse cardiac events (MACE [death, readmission for myocardial infarction, unplanned revascularization]) (HR, 1.03; 95% CI, 0.86–1.25). For long vs. short LOS there were significant increases in adjusted mortality (HR, 2.30; 95% CI, 1.72–3.07) and MACE (HR, 1.75; 95% CI, 1.44–2.12). Significantly increased 30-day mortality and MACE were seen for patients with a very short LOS (one to two days) vs. three- to four-day LOS.
"Early, but not very early (<48 hours), discharge may be safe among selected older patients with STEMI," the authors write.
One author disclosed financial ties to the pharmaceutical industry.