Statins May Speed Wound Healing Post-Surgery

the MPR take:

A retrospective study in the Annals of Thoracic Surgery points to statins as possibly having a positive benefit in surgical wound healing. In the review of 20 studies on statins and surgical wound healing, statin use led to a 30% faster rate of wound epithelialization and an 80% greater wound-breaking strength with faster wound healing rates (13.0 days vs. 18.7 days, P<0.0001). While one of the two studies involving humans found no benefit for patients undergoing hernia surgery, it did not account for the use of other blood-thinning medications that could have impacted the results. It is believed that statins reduce the activity of white cell production without impacting its function in the healing process.

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Statins May Speed Wound Healing Post-Surgery

Statins, the widely used cholesterol-lowering drugs, may have a role in surgical wound healing, a new analysis suggests. They demonstrated various mechanisms by which statins can lower inflammation, improve the mechanical strength of a healing wound, promote the growth of blood vessels and reduce healing time. Most were animal or laboratory tissue studies, but two were studies in humans.

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