Rash Patterns Suggest B19 Virus in Adults
(HealthDay News) — Primary parvovirus B19 infection is associated with polymorphous skin manifestations in adults, according to research published in the July issue of the Journal of the American Academy of Dermatology.
Valentia Mage, MD, from the Université René Descartes in Paris, and colleagues conducted a retrospective, descriptive study of 29 patients (17 women and 12 men) to evaluate the cutaneous presentations associated with parvovirus B19 primary infection in adults.
The researchers found that the basic skin lesions associated with parvovirus B19 primary infection were mostly erythematous (86 percent) and frequently purpuric (69%). Pruritus accompanied the rash in almost half (48%) of cases. The rash commonly occurred on the legs (93%), trunk (55%), arms (45%), and, less often, the face (20%). Four distinct patterns, sometime overlapping, were identified: exanthema, in some cases, reticulated and annular (80%); periflexural pattern (28%); gloves-and-socks pattern (24%); and palpable purpura (24%).
"Our findings suggest that primary parvovirus B19 infection is associated with polymorphous skin manifestations with four predominant, sometimes overlapping, patterns," the authors write. "The acral or periflexural distribution of the rash and the presence of purpuric or annular/reticulate lesions are highly suggestive of parvovirus B19 infection."