Do IBD Flares Increase MI Recurrence Risk?

the MPR take:

Patients with active inflammatory bowel disease (IBD) have a greater risk of recurrent myocardial infarction (MI) following first-time MI compared to non-IBD patients, reports a new study in Circulation: Cardiovascular Quality and Outcomes. Using national registries in Denmark, 1,030 patients with IBD that were diagnosed with first-time MI between 2002–2011 were identified and categorized according to disease activity stages of flare (120 days), persistent (>120 days) activity, or remission. Compared with non-IBD patients, the odds ratio of death during hospitalization or within 30 days of discharge was 3.29 (95% CI, 1.98–5.45) for patients in IBD flares, 1.62 (95% CI, 0.95–2.77) for persistent activity, and 0.97 (95% CI, 0.78–1.19) for remission. IBD flares were associated with an increased risk of recurrent MI (95% CI, 1.79–5.32), all-cause mortality (95% CI, 1.61–3.15), and a composite end point of recurrent MI, cardiovascular death, and stroke (95% CI, 1.35–3.06) vs. the non-IBD patients; no increased risk was identified in patients in remission. After first-time MI, known risk factors for MI should be assessed in IBD patients with remission as a goal to further reduce recurrent MI risk.

Prognosis After First-Time Myocardial Infarction in Patients With Inflammatory Bowel Disease Accordi
Do IBD Flares Increase MI Recurrence Risk?

We examined the effect of active IBD on major adverse cardiovascular outcomes after myocardial infarction (MI).Methods and Results- In nationwide registries, we identified 86 790 patients with first-time MI from the period 2002 to 2011. Odds ratio of death during hospitalization or within 30 ...

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