Bariatric Surgery Benefits Diabetes Over Long Term
(HealthDay News) — Long-term follow-up shows that, in patients with type 2 diabetes, bariatric surgery is associated with greater diabetes remission and fewer diabetes-related complications than usual care, according to a study published in the June 11 issue of the Journal of the American Medical Association, a theme issue on diabetes.
Lars Sjöström, MD, PhD, from the Sahlgrenska University Hospital in Gothenburg, Sweden, and colleagues used data from participants in the Swedish Obese Subjects study and national registers to assess long-term outcomes for remission and diabetes-related complications among diabetes patients. The study participants underwent either bariatric surgery (adjustable or nonadjustable banding [61 patients], vertical banded gastroplasty [227 patients], or gastric bypass [55 patients] procedures) or usual obesity and diabetes care (control group).
The researchers found the diabetes remission rate two years after surgery to be 16.4% for control patients and 72.3% for bariatric surgery patients (odds ratio [OR], 13.3; P<0.001). The diabetes remission rates decreased at 15 years to 6.5 and 30.4%, respectively (OR, 6.3; P<0.001). The cumulative incidence of microvascular complications in long-term follow-up was 41.8 per 1,000 person-years for controls and 20.6 per 1,000 person-years in the surgery group (hazard ratio [HR], 0.44; P<0.001), whereas macrovascular complications were seen in 44.2 per 1,000 person-years for control patients and 31.7 per 1,000 person-years for the surgical group (HR, 0.68; P=0.001).
"These findings require confirmation in randomized trials," the authors caution.
Several authors disclosed financial ties to the pharmaceutical industry.