Labor And Delivery

For Postpartum Hemorrhage, Carbetocin Similar to Oxytocin

July 05, 2018

Heat-stable carbetocin non-inferior for preventing blood loss of 500 ml, use of other uterotonic agents

Data Needed on New Type 2 Diabetes Therapies in Pregnancy

July 02, 2018

Scarce data on new glucose-lowering agents, with high risk for bias toward negative outcomes

Preservative-Free, Generic Version of Makena Now Available

By June 28, 2018

Hydroxyprogesterone Caproate is used to lower the risk of preterm birth in women with a singleton pregnancy who have a history of singleton spontaneous preterm birth.

No Causal Effect of 25(OH)D on Gestational HTN, Preeclampsia

June 21, 2018

"No strong evidence was found to support a causal effect of vitamin D status on gestational hypertension or preeclampsia," the authors write.

Antifungal Use During Pregnancy and Risk of Stillbirth: What's the Link?

By June 13, 2018

Based on the findings, it was concluded that fluconazole use during pregnancy was not associated with significantly increased risks of stillbirth or neonatal death. However, the authors cautioned that the confidence intervals were wide and neither result was statistically significant.

Recommendations for Managing Postpartum Pain Published

May 23, 2018

Impact of medications on mother-infant dyad should be considered, as many women breastfeed

FDA: Possible Risk of Neural Tube Birth Defects With Certain HIV Meds

By May 18, 2018

The Agency has received reports of serious neural tube birth defects involving the brain, spine, and spinal cord in babies born to women who received dolutegravir for HIV treatment.

CDC: Number of US Births Dropped to 30-Year Low in 2017

May 17, 2018

For teenagers aged 15 to 19 years, the birth rate decreased 7% in 2017 to 18.8 births per 1,000 women, with decreases in the rates for younger and older teenagers (15 to 17 and 18 to 19, respectively).

Acupuncture Doesn't Up Live Birth Rate for Women Having IVF

May 16, 2018

The researchers found that live births occurred in 18.3 and 17.8% of women receiving acupuncture and sham control, respectively (risk difference, 0.5% [95% confidence interval, −4.9 to 5.8%]; relative risk, 1.02 [95% confidence interval, 0.76 to 1.38]).

Glyburide Compared With Insulin for First-Line Tx of Gestational Diabetes

May 02, 2018

Frequency of primary outcome was 27.6 and 23.4 percent in glyburide and insulin groups, respectively

Fetal Inflammation May Play Role in Preterm Labor

April 26, 2018

T cells from preterm infants stimulated contractility of the uterine myometrium through interferon-γ and tumor necrosis factor-α. In mouse fetuses, adoptive transfer of activated T cells resulted in pregnancy loss.

ACOG: Revised Committee Opinion on Postpartum Care Released

By April 25, 2018

Previously, ACOG had recommended a comprehensive postpartum visit occur within the first 6 weeks after birth.

CDC: Birth Rate for 10- to-14-Year-Olds at Record Low in 2016

April 25, 2018

During the same time period, birth rates declined for females aged 10 to 14 years for all race and Hispanic-origin groups, with non-Hispanic black females having the largest decline.

Point-of-Care Test for Assessing Risk of Spontaneous Preterm Birth Approved

By April 20, 2018

The test detects placental alpha microglobulin-1 (PAMG-1) in patients presenting with signs and symptoms of preterm labor.

Cimzia Label Update Provides New Information for Women of Childbearing Age

By March 22, 2018

Data added to the labeling includes first-of-their-kind pharmacokinetic studies demonstrating negligible to low transfer of CIMZIA through placenta and minimal transfer to breast milk from mother to infant.

Is It Safe for Women to Eat or Drink During Labor?

March 01, 2018

"Allowing women ad lib oral intake during labor does not increase adverse maternal or neonatal outcomes. It stands to reason that allowing such intake could increase patient satisfaction," the authors write.

Ready-to-Use Makena Formulation Approved to Reduce Preterm Birth Risk

By February 15, 2018

Makena was the first FDA-approved treatment option for pregnant women who have had prior spontaneous preterm birth.

Antihypertensive Use During Delivery Evaluated Among Preeclamptic Women

February 15, 2018

The researchers found that overall, 105,409 women received a hypertensive agent. Receipt of oral labetalol increased from 20.3% in 2006 to 31.4 percent in 2014 for all patients with preeclampsia.

Is There Any Link Between Ultrasound Exposure and Autism?

February 14, 2018

The ASD group had a shorter duration of ultrasound exposure than the typical development group during the first (290.4 versus 406.4 seconds) and second (1,687.6 versus 2,011 seconds) trimesters. Greater mean depth of ultrasonographic penetration was seen in the ASD group versus the developmental delay group in the first trimester (12.5 versus 11.6 cm).

Inhaled Nitric Oxide Examined for Lowering Neonate Mortality

February 09, 2018

The researchers identified 993 neonates (2.6%) who received iNO among 37,909 neonates in the study sample. A total of 971 patients were included in each of the two matched cohorts.

Fetal Risk After Pregnancy Exposure to Natalizumab Examined

February 08, 2018

And, natalizumab washout period is only predictor of relapse occurrence during pregnancy

USPSTF: Screening for Syphilis in Pregnant Women Beneficial

February 07, 2018

Draft recommendation indicates considerable net benefit to screening for syphilis infection

Low-Carb Diets Linked to Increased Risk of Neural Tube Defects

February 06, 2018

First study to assess the effect of carb intake on neural tube defects, postfortification with folic acid

Edurant Dosing Recommendations Updated for Pregnant HIV Patients

By February 02, 2018

Lower exposures of rilpivirine were observed during pregnancy, therefore viral load should be monitored closely.

Probiotic Milk Intake Examined for Preterm Delivery, Preeclampsia Risk

January 24, 2018

On the other hand, a lower risk of preterm delivery was significantly associated with probiotic intake during early pregnancy but not before or during late pregnancy (adjusted odds ratio, 0.79).

ADHD Medication Use Increasing Among Reproductive-Aged Women

By January 18, 2018

ADHD medication prescriptions are increasingly common among privately insured, reproductive-aged women.

Vitamin D and Reproductive Treatment Outcomes: What's the Link?

November 17, 2017

The researchers found that live birth was more likely in women replete with vitamin D versus those with vitamin D deficiency or insufficiency.

Psychostimulant Use Linked to Preeclampsia, Preterm Birth

November 15, 2017

Small increased relative risk of preeclampsia, preterm birth; absolute risk increases are small

Antibiotic Combo for Cesarean Prophylaxis Linked to Better Maternal Outcomes

November 14, 2017

Improved maternal outcomes when azithromycin is added to cephalosporin for infection prophylaxis