Immunization

BCG Vaccine Tied to Reduced Hyperglycemia in Type 1 Diabetes

June 22, 2018

Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis

HPV Vaccine Under Priority Review for Expanded Age Range

By June 13, 2018

Specifically, the types the vaccine protects against are HPV 16, 18, 31, 33, 45, 52, 58 (which cause ~90% of cervical cancer cases worldwide), and types 6 and 11 which case genital warts.

CDC Issues Updated Advisory Regarding Outbreaks of Hepatitis A

By June 11, 2018

Of the 2500 cases of hepatitis A infection reported between January 2017 and April 2018, 68% were among persons who reported drug use (injection and non-injection), homelessness, or both.

Increase in Requirement for Flu Vaccines at Non-VA Hospitals

June 06, 2018

The researchers found that mandatory influenza vaccination requirements for HCP increased from 37.1% in 2013 to 61.4% in 2017 among all responding hospitals.

No New Adverse Events Reported for DTaP Vaccination

June 04, 2018

The researchers found that 50,157 reports were received by VAERS after DTaP vaccination; 87.7% reported concomitant administration of other vaccines and 11.2% of reports were serious.

CDC: Administration Errors Reported With New Shingles Vaccine

By May 30, 2018

Between October 20, 2017 and February 20, 2018, the Vaccine Adverse Event Reporting System (VAERS) received 155 reports involving RZV, with 13 (8%) involving an administrative error.

Herpes Zoster Vaccination Rates Assessed Among People Living With HIV

By May 28, 2018

The authors found that vaccination rates varied between 1.5% and 42.4% at the 6 institutions assessed and that 21.3% of eligible patients at the University of Colorado received HZV prior to the intervention.

Prevnar 13 Linked to Reduced Risk of CAP Hospitalization in Older Patients

By May 24, 2018

PCV13, marketed as Prevnar 13, was evaluated in a test-negative case-control study in real-world conditions where patients were administered pneumococcal vaccination as advised by their healthcare providers.

HPV Vaccination Coverage, Trends by Age Examined in US

By May 24, 2018

Provider-verified vaccination records obtained from a pilot study conducted in 14-29-year-old patients were utilized to determine the sensitivity and specificity of the self/parent-reported vaccination data.

Need for Gonorrhea Vaccine Highlighted in Light of Global Disease Burden

By May 22, 2018

Dr Vincent also states that target groups should be considered in vaccine development and adds, "It is generally thought that the best target group would be girls and boys aged 9-13, preferably before sexual debut, similar to the HPV vaccination program."

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

By May 22, 2018

The advisory comes early as physicians are currently placing vaccine orders.

Robust Immune Responses for Herpes Zoster Subunit Vaccine

May 21, 2018

The researchers identified a humoral response in 97.8 and 2% of HZ/su and placebo recipients, respectively, after vaccination.

HPV Vaccination May Offer Protection Against Cervical Precancer

By May 11, 2018

The authors concluded, "There is high-certainty evidence that HPV vaccines protect against cervical precancer in adolescent girls and young women aged 15 to 26," while also indicated that future studies should have long-term follow-up.

Vaccine for Chikungunya Prevention Gets Fast Track Designation

By May 04, 2018

There are currently no approved treatments or vaccines available for chikungunya, a virus transmitted through mosquito bites.

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

May 01, 2018

The researchers found that even relatively low-efficacy influenza vaccines can have a high impact, especially with optimal distribution across age groups. In order to minimize mortality and DALYs, the optimal distribution of the vaccine uptake shifts toward the elderly as vaccine efficacy declines.

FDA to Review Fluzone Quadrivalent 0.5mL Dose for Younger Patients

By April 27, 2018

The sBLA included clinical data from a Phase 4 study that enrolled nearly 2000 children and assessed the safety and immunogenicity of the 0.5mL dose.

CDC: Recommendations on the Use of Heplisav-B Published

By April 23, 2018

Benefits of protection with 2 doses administered over 1 month make the vaccine an important option for prevention of HBV.

MenB Vaccine Gets Breakthrough Tx Designation for Kids Ages 1 to 9 Years

By April 23, 2018

The Breakthrough designation was based on data from Phase 2 studies which assessed the safety and efficacy of the vaccine in this patient population.

Efficacy of Adjuvanted vs Conventional Quadrivalent Flu Vaccine Compared

By April 20, 2018

MF59 adjuvanted, quadrivalent influenza vaccine (aQIV) was found to be more efficacious in preventing influenza than a non-adjuvanted conventional influenza vaccine in children aged 6 through 23 months.

Review: Treatment Recommendations for Biological Disasters

By April 17, 2018

The Centers for Disease Control and Prevention (CDC) classifies key biological agents into three categories: A, B, and C.

Personalized Cancer Vaccine Looks Promising in Early Study

By April 12, 2018

The researchers enrolled 25 platinum-pretreated, immunotherapy-naïve patients with recurrent advanced epithelial ovarian cancer (EOC) for the trial.

A Zika vaccine could virtually eliminate prenatal infections

April 11, 2018

Zika virus shown to be of moderate to high efficacy in eliminating prenatal infections.

Stronger Recommendations by PCPs for Herpes Zoster Vaccination Needed, Says Study

By April 09, 2018

From January to March 2017, the researchers distributed a cross-sectional online survey to all physicians in the Division of General Internal Medicine and Clinical Innovation at NYULH, across 5 different practice settings. A total of 138 (out of 530) responded (26%).

MenACWY-TT Vaccine Evaluated in Patients With Anatomic/Functional Asplenia

By April 09, 2018

Risk of meningococcal disease up in patients with anatomic/functional asplenia.

Herpes Zoster in Healthy Children Linked to Varicella-Zoster Vaccination

By April 05, 2018

Each of the 7 children received varicella zoster vaccination between 12 and 14 months of age.

Zika Vaccine Could Essentially Eliminate Prenatal Infection

April 03, 2018

The researchers found that for a base-case vaccine efficacy of 75% and vaccination coverage of 90%, immunizing females aged 9 to 49 years would reduce the incidence of prenatal infections by at least 94%, depending on the country-specific Zika attack rate.

Recombinant Influenza Vaccine Found to Be Safe in Children

April 02, 2018

The researchers found that both vaccines were well tolerated in both 6- to 8-year-olds and 9- to 17-year-olds. There were no vaccine-related adverse events in the 6 months of follow-up.

2018 Vaccination Schedule: Adults

April 02, 2018

This schedule indicates the recommended age groups and medical indications for routine administration of currently licensed vaccines for persons 19 years and older.

Children With ASD, Younger Siblings Are Undervaccinated

March 28, 2018

Vaccination rates were significantly lower among younger siblings of children with ASD

2018 Vaccination Schedule: 0-18 Years of Age

March 28, 2018

This schedule indicates the recommended ages for routine administration of currently licensed childhood vaccines for children 0-18 years of age.