Rebecca Wittenberg, PharmD, spoke to MPR at IDWEEK 2017 about the research paper she co-authored on posaconazole and hypertension, hypokalemia risks.
MPR spoke with Gerome Escota, MD, at IDWeek 2017, who co-authored a review at a large urban outpatient center to identify the proportion of appropriate statin use.
MPR caught up with Mark Shaefer, PharmD, at IDWEEK 2017 to speak about the research he led concerning abacavir use and myocardial infarction (MI) risks.
Effective treatment of latent tuberculosis infection is key to TB control efforts and approaching the goal of TB elimination, the authors reported.
Study patients were randomized to 1-hour IV fosfomycin 6g infusion every 8 hours (18 g total daily dose) or IV piperacillin/tazobactam 4.5g infused over 1 hour every 8 hours for a fixed 7 days.
Researchers compared the integrated safety outcomes between delafloxacin and vancomycin/aztreonam from two Phase 3 ABSSSI studies.
Clinical and demographic profiles of patients were compared on those who completed the 9H vs. 3HP regimens with a focus on adverse events, which can commonly cause treatment discontinuation.
The ceftriaxone + doxycycline regimen has been favored in light of 'recent concerns of increased cardiovascular risk associated with azithromycin
The researchers sought to determine the type and frequency of hormonal contraceptives and ART prescribed to women with HIV infection and prevalence of resulting drug to drug interaction potential.
Traditional combination ART consists of 2 nucleoside reverse transcriptase inhibitors + 1 protease inhibitor; this prospective study of 274 pregnant women infected with HIV compared their viral load near delivery after receiving traditional cART.
Retrospective chart reviews were conducted for Black, genotype 1 (GT1), HIV/HCV co-infected patients treated with ledipasvir/sofosbuvir (LDV/SOF) at 3 hospitals.
The researchers compared the effectiveness of oral beta-lactams to fluoroquinolones in the treatment of Enterobacteriaceae bloodstream infections (EBSI) in adult patients.
Intravenous (IV) antibiotics such as CPT is indicated for ABSSSIs "but real world clinical comparative data is limited."
The authors gathered clinical and demographic data from the University of Kentucky Center for Clinical and Translational Science Enterprise Data Trust, for adults who received TZP+VAN or CFP+VAN for ≥48 hours in the ICU.
To investigate the efficacy of telavancin in the treatment of bacteremia and infective endocarditis, the authors looked at data from the Telavancin Observational Use Registry, which reports on outcomes of patients treated with telavancin in clinical practice.
A total of 1,042 patients with infection were randomly assigned to receive either intravenous/oral DLX monotherapy or VAN (15mg/kg) with AZ for 5 to 14 days.
The study authors sought to contribute to the evidence base on gender differences in virologic and immunologic responses to ART in treatment-naïve individuals.
Participants included 464 hospitalized adults with cUTI or AP diagnosis, randomly assigned to be administered either ZTI-01 or piperacillin/tazobactam for a fixed 7 days.
Omadacycline is a novel, broad-spectrum aminomethylcycline related to tetracyclines; the OASIS phase 3 trial investigated whether it was non-inferior to linezolid.
Researchers assessed the risk of febrile seizures following inactivated influenza vaccine and pneumococcal conjugate vaccine-13 during 2013-14 and 2014-15 flu seasons.
Rates of viral failure were compared in HIV patients initiated on dolutegravir-based vs. other guideline recommended regimens in clinical care.
Two sequential administration groups were compared by demonstrating the antibody response curve and the reverse cumulative distribution curve analyses by serotype.
For adults aged ≥65 years, seasonal flu epidemics pose significant disease burden annually and not many vaccines are specifically formulated for this patient population.
At baseline, the viral load, CD4 cell counts, renal laboratory parameters, and bone mineral density (BMD) were comparable between the 2 treatment arms for blacks and non-blacks.
The researchers conducted the study because protection against herpes zoster has been "shown to wane with time" and effect sizes "can be imprecise".
Appropriate diagnosis was defined as confirmed UTI which included: pyuria, a positive urine culture, and lower urinary tract symptoms.