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The FDA is investigating new preliminary data suggesting an increased risk of serious skin reactions from the anti-epileptic drugs phenytoin and fosphenytoin if they are taken by Asian patients who are positive for the human leukocyte antigen allele HLA-B*1502.

FDA is alerting patients and healthcare professionals about the potential danger of using topical anesthetics to relieve pain before having mammography or other medical procedures.

The Institute for Safe Medication Practices (ISMP) is warning about mix-ups between the trade name of one drug and the generic name of another. Purinethol® (mercaptopurine), is the trade name of a potent antimetabolite used in oncology. Propylthiouracil is an anti-thyroid agent that only comes in generic form.

The Institute for Safe Medication Practices (ISMP) is warning again about the possibility of mix-ups between ephedrine and epinephrine.

In a recent report, the Institute for Safe Medication Practices warned about the possibility of prescribing and administering the wrong dose of alteplase when the indication for the drug is not specified.