HealthDay News — Patients with vascular malformations (VAMs) have increased pain and psychosocial distress, compared with the general U.S. population, according to a review published online March 21 in JAMA Dermatology.

Henry L. Nguyen, MD, from the Mayo Clinic in Rochester, Minn., and colleagues conducted a systematic literature review to identify studies that used validated tools to compare the health-related quality of life (HRQoL) of persons with VAMs with the general U.S. population. 

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The researchers identified 11 studies representing 692 patients with VAMs, but only 6 studies (320 patients) were included in the meta-analysis. Compared to the general U.S. population, those with VAMs had lower 36-Item Short-Form Health Survey scores for bodily pain (P=0.02) and mental health (P=0.03).

“Pain and psychological morbidity are associated with poorer HRQoL and may serve as indicators for quality of life,” the authors write.

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