Boehringer Ingelheim and Lilly announced the launch of Synjardy XR (empagliflozin and metformin HCl extended-release) tablets as adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes when treatment with both empagliflozin and metformin HCl is appropriate.

Synjardy XR combines empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and metformin, a biguanide. Empagliflozin is also indicated to reduce the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease but the efficacy of Synjardy XR has not been established for this indication.  

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The Food and Drug Administration (FDA) initially approved Synjardy XR in December 2016. Both Synjardy and Synjardy XR should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis. It carries a boxed warning regarding metformin-associated lactic acidosis. 

Synjardy XR is available in 5mg/1000mg and 12.5mg/1000mg strength tablets in 180-count bottles, and as 10mg/1000mg and 25mg/1000mg strength tablets in 30-count and 90-count bottles. Synjardy is already available as 5mg/500mg, 12.5mg/500mg, 5mg/1000mg, and 12.5mg/1000mg strength tablets in 60- and 180-count bottles.

For more information call (800) 542-6257 or visit