Patients with Clostridium difficile infection (CDI) are twice as likely to be readmitted to the hospital compared to patients without this infection, according to a new research. The results appear in the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

Teena Chopra, MD, MPH, from the Detroit Medical Center, and colleagues reviewed 51,353 all-cause hospital discharges from January 1 to December 31, 2012. A total of 615 patients (1%) were discharged with a CDI diagnosis; CDI was present on admission for 318 patients and 297 were diagnosed with the infection during their hospitalization.

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Only 14.4% of all-cause discharge patients were readmitted to the hospital after 30 days, compared to 30.1% of CDI patients. Length of stay (LOS) upon readmission was significantly greater in the CDI patients, who stayed an average of 4.4 additional days for community-onset CDI and 6.4 days for hospital-onset CDI compared to non-CDI readmissions.

Effective antibiotic stewardship should be universal across the healthcare system to reduce the rates of CDI and CDI-related readmissions, Dr. Chopra added.

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