HealthDay News – There currently is no evidence of intrauterine infection caused by vertical transmission in women who develop 2019 novel coronavirus disease (COVID-19) pneumonia in late pregnancy, according to research published online February 12 in The Lancet.
Huijun Chen, PhD, from Wuhan University in China, and colleagues conducted a retrospective review of clinical records, laboratory results, and chest computed tomography scans for 9 pregnant women with laboratory-confirmed COVID-19 admitted from January 20 to January 31, 2020.
The researchers note that all the patients had a cesarean section in the third trimester. Seven patients presented with fever. Cough, myalgia, sore throat, and malaise were also observed (4, 3, 2, and 2 patients, respectively). In 2 cases, fetal distress was monitored. Lymphopenia was seen in 5 patients. Increased aminotransferase concentrations were seen in 3 patients. As of February 4, 2020, none of the patients developed severe COVID-19 pneumonia or died. There were 9 recorded live births, all of which had a 1-minute Apgar score of 8 to 9 and a 5-minute Apgar score of 9 to 10. In newborn babies, there was no neonatal asphyxia observed. In 6 patients tested for severe acute respiratory syndrome coronavirus 2, amniotic fluid, cord blood, neonatal throat swab, and breast milk samples were all negative for the virus.
“We believe that the findings reported here are important for understanding the clinical characteristics and vertical transmission potential of COVID-19 infection in pregnant women,” the authors write.