Further analyses over an 18-year follow-up revealed that individuals who reported lifetime marijuana use of ≥100 times had a 40% higher chance of developing prediabetes–but not diabetes–compared to never users. Researchers noted that BMI and waist circumference did not influence these associations.

Study authors concluded that it is unclear how marijuana use can increase an individual’s risk for prediabetes but not diabetes. The occurrence of prediabetes in middle adulthood was significantly higher for those who reported using marijuana at least 100 time by young adulthood. Overall, marijuana use was not associated with incidence or presence of diabetes after accounting for potential confounding factors but was associated with the development and prevalence of prediabetes.

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