(HealthDay News) – For survivors of acute myocardial infarction (AMI), residential proximity to a major roadway at the time of AMI is linked to an increased risk of 10-year mortality.

Joshua I. Rosenbloom, MPH, from Harvard Medical School in Boston, and colleagues analyzed data from 3,547 patients hospitalized for AMI who participated in the Determinants of Myocardial Infarction Onset Study. Addresses were geocoded and the distance to the nearest major roadway was noted.

After 10 years of follow-up, the researchers identified 1,071 deaths. After adjusting for personal, clinical, and neighborhood-level variables, compared with living >1,000m from a major roadway, there was an increased risk of all-cause mortality associated with living ≤100m (hazard ratio [HR], 1.27; 95% confidence interval [CI], 1.01–1.6), 100–≤200m (HR, 1.19; 95% CI, 0.93–1.6), and 200– ≤1,000m (HR, 1.13; 95% CI, 0.99–1.3) from a major roadway (Ptrend=0.015).

“In this multicenter study, living close to a major roadway at the time of AMI was associated with increased risk of all-cause 10-year mortality; this relationship persisted after adjustment for individual and neighborhood-level covariates,” the authors write.

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