The Food and Drug Administration (FDA) is informing that Victrelis (boceprevir; Merck) 200mg capsules will be discontinued.

Victrelis is a HCV NS3/4A protease inhibitor indicated for the treatment of chronic hepatitis C genotype 1 infection, in combination with peginterferon alfa and ribavirin in adult patients with compensated liver disease, including cirrhosis, who are previously untreated or who have failed previous interferon and ribavirin therapy including prior null responders, partial responders, and relapsers.

RELATED: Hepatitis C Virus Treatments

Victrelis works by covalently, yet reversibly, binding to the NS3 protease active site serine (S139) through an (alpha)-ketoamide functional group to inhibit viral replication in HCV-infected host cells.

Victrelis is estimated to be available until December 2015. Discontinuation of Victrelis is not related to any product safety or efficacy matters.

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