Abacavir and Lamivudine Tablets are indicated in combination with other antiretroviral drugs for the treatment of HIV-1 infection. They work to reduce the viral load and increase the number of CD4+ cells to help fight off other infections.
Abacavir and Lamivudine are both nucleoside analogue HIV-1 reverse transcriptase inhibitors. Abacavir is converted by cellular enzymes to active metabolite CBV-TP, which inhibits the activity of HIV-1 reverse transcriptase both by competing with the natural substrate dGTP and by its incorporation into viral DNA. Lamivudine is phosphorylated into its active metabolite 3TC-TP, which inhibits reverse transcriptase via DNA chain termination after incorporation of the nucleotide analogue.
Abacavir and Lamivudine Tablets are available as a 600mg/300mg strength in 30-count bottles.
For more information call (888) 838-2872 or visit TevaGenerics.com.