Ivermectin cream is a semi-synthetic derivative isolated from the fermentation of Streptomyces avermitilis that belongs to the avermectin family of macrocyclic lactones. It is indicated to treat inflammatory lesions of rosacea.
Ivermectin was initially approved by the FDA in December 2014. In a Phase 3 head-to-head study vs metronidazole 0.75% cream, ivermectin cream proved more effective from Week 3 onward.
Perrigo reached a settlement with Galderma Laboratories and Nestle Skin Health concerning this generic version of Soolantra.
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