Nexium is approved as triple therapy (with amoxicillin + clarithromycin) for H. pylori eradication in duodenal ulcer disease, short-term treatment and maintenance of healing of erosive esophagitis (EE), symptomatic GERD, short-term treatment of EE due to acid-mediated GERD in infants 1 month to <1 year, to reduce risk of NSAID-associated gastric ulcer, and as long-term treatment of pathological hypersecretory conditions (eg, Zollinger-Ellison syndrome).
Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell. By specifically acting on the proton pump, esomeprazole blocks the final step in acid production, thus reducing gastric acidity.
Esomeprazole Magnesium Delayed-Release Capsules will be available in 20mg and 40mg strengths.
For more information call (800) RX-MYLAN or visit Mylan.com.