The first authorized generic version of Azopt® 1% (brinzolamide ophthalmic suspension) has been made available by Teva Pharmaceuticals USA, Inc.

Brinzolamide ophthalmic suspension 1%, a carbonic anhydrase inhibitor, is indicated for the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Following topical ocular administration, brinzolamide inhibits aqueous humor formation and reduces elevated intraocular pressure.

Brinzolamide ophthalmic suspension 1% may be used concomitantly with other topical ophthalmic agents to lower intraocular pressure. The drugs should be administered at least 10 minutes apart if more than 1 topical ophthalmic drug is used.

The most common adverse reactions associated with treatment include blurred vision and bitter, sour or unusual taste.


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The product is supplied in 10mL and 15mL bottles containing 10mg/mL of brinzolamide.

Reference

Teva announces launch of first generic version of Azopt® (brinzolamide ophthalmic suspension) 1%, used to treat high pressure inside the eye, in the United States. [press release]. Tel Aviv, Israel and Parsippany, NJ: Teva Pharmaceuticals USA, Inc.; March 8, 2021.