Zemplar Injection, a vitamin D analog, is indicated for secondary hyperparathyroidism due to chronic renal failure. The biological effects of paricalcitol are mediated through binding of the vitamin D receptor, which results in the selective activation of the vitamin D responsive pathways. Vitamin D and paricalcitol have been shown to reduce parathyroid hormone levels by inhibiting parathyroid hormone synthesis and secretion.
Paricalcitol Injection is available as 2mcg, 5mcg, and 10mcg strengths.
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