West-Ward, the U.S. division of Hikma Pharmaceuticals, announced the availability of Mitigare (colchicine) capsules and its authorized generic for the prophylaxis of gout flares in adults.
Colchicine is thought to block neutrophil-mediated inflammatory responses induced by monosodium urate crystals in synovial fluid. Colchicine disrupts the polymerization of β-tubulin into microtubules, thereby preventing the activation, degranulation, and migration of neutrophils to sites of inflammation. Colchicine also interferes with the inflammasome complex found in neutrophils and monocytes that mediates interleukin-1β activation.
Mitigare and its authorized generic are available as 0.6mg strength capsules in 100- and 1000-count bottles.
For more information call (800) 631-2174 or visit West-Ward.com.