Astelin is indicated for the treatment of the symptoms of seasonal allergic rhinitis in adults and children aged ≥5 years old, and for the treatment of symptoms of vasomotor rhinitis in adults and adolescents aged ≥12 years old. Azelastine HCl, a phthalazinone derivative, exhibits histamine H1-receptor antagonist activity in isolated tissues, animal models, and humans. Its major metabolite, desmethylazelastine, also possesses H1-receptor antagonist activity.
Azelastine HCl Nasal Solution is available as a 0.1% strength.
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