Diclofenac Sodium is a non-steroidal anti-inflammatory drug (NSAID) that is indicated for the relief of osteoarthritis of joints amenable to topical treatment (eg, knees, hands).
The mechanism of action is similar to that of other NSAIDs. Diclofenac inhibits the enzyme, cyclooxygenase (COX), an early component of the arachidonic acid cascade, resulting in the reduced formation of prostaglandins, thromboxanes and prostacyclin. It is not completely understood how reduced synthesis of these compounds results in therapeutic efficacy.
Diclofenac Sodium Topical Gel 1% is supplied as a 100g tube.
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