Actavis announced that it has received final FDA approval for its Abbreviated New Drug Application (ANDA) of Clonidine Transdermal System, the generic version of Boehringer Ingelheim’s Catapres-TTS. Catapres-TTS is indicated for the treatment of hypertension.

Clonidine is a central alpha-agonist that stimulates alpha-adrenoreceptors in the brain stem. This action results in reducedsympathetic outflow from the central nervous system and in decreases in peripheral resistance, renal vascular resistance, heart rate, and blood pressure.

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Catapres-TTS is available in 0.1mg/day, 0.2mg/day, and 0.3mg/day (for 7 days).

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