Cumberland announced the publication of new clinical data in BMC Pediatrics showing that treatment with Caldolor (ibuprofen) Injection led to significant fever reduction in hospitalized children.

Oral ibuprofen is commonly administered in hospitals to treat pediatric patients who develop fevers but those who present to the emergency department or are undergoing surgery are usually unable to take their medications by the oral route. The randomized, open-label study (n=103) evaluated the safety, efficacy, and pharmacokinetics of intravenous ibuprofen in pediatric patients aged ≥6 months with fever ≥101.0 degrees Fahrenheit. 

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Findings showed that a 10mg/kg dose of intravenous ibuprofen resulted in a significant reduction of temperature for pediatric patients serving as an effective option for reducing fever in the pediatric population. 

Caldolor, a non-steroidal anti-inflammatory drug (NSAID), is indicated in adults and pediatric patients for the management of mild to moderate pain and management of moderate to severe pain as an adjunct to opioid analgesics, as well as the reduction of fever. It is available as a 100mg/mL strength 8mL single-dose vials in 25-count cartons. 

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