Chimerix announced final data from CMX001 Study 201, a Phase 2 study evaluating CMX001 for the prevention of cytomegalovirus in hematopoietic cell transplant recipients. 

CMX001 Study 201 was a randomized, placebo-controlled study.  Two hundred thirty subjects were randomized (3:1) to receive CMX001 or placebo in five sequential, dose-escalating cohorts.  Subjects were dosed either once weekly or twice weekly for 9–11 weeks until post-transplant week 13, with a 4–8 week follow-up period. 

CMX001 is a broad spectrum, Lipid-Antiviral-Conjugate that delivers high intracellular levels of the active antiviral agent cidofovir-diphosphate and has broad spectrum activity against dsDNA viruses.

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