Proteo announced that the FDA has granted orphan drug designation to Elafin for the treatment of pulmonary arterial hypertension. Elafin is a copy of a naturally occurring human anti-inflammatory substance. It is a natural antagonist of the tissue destroying proteases that participate in the inflammatory mechanism.

The tolerability of intravenously administered recombinant Elafin has been demonstrated in a Phase 1 clinical trial.

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