Anticogulant Reversal Agent Fast Tracked by FDA

Perosphere announced that the Food and Drug Administration (FDA) has granted Fast Track designation to PER977, an anticoagulant reversal agent.

PER977 is a small synthetic water-soluble new molecular entity that directly combines with new oral anticoagulants (eg, direct Xa- and IIa- inhibitors), fondaparinux, low molecular weight heparins and unfractionated heparins thus enabling rapid re-establishment of a normal blood coagulation state. This reversal effect is due to direct binding to the anticoagulant molecule with no binding to blood coagulation factors or to other proteins in the blood.

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Currently, PER977 is undergoing clinical development as a sterile, intravenous injection.

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