(HealthDay News) — Vitamin D deficiency is associated with increased odds of asthma exacerbations, according to a study published in the December issue of Allergy.

Ronit Confino-Cohen, MD, from the Meir Medical Center in Kfar Saba, Israel, and colleagues examined the correlations between serum 25-hydroxyvitamin D (25[OH]D) level and asthma in a cohort of Israeli adults aged 22–50 years. Participants with physician-diagnosed asthma and asthma exacerbation were identified.

The researchers found that 6.9% of the 308,000 participants with at least one vitamin D measurement had physician-diagnosed asthma, compared with 5.7% in the general population. Serum 25(OH)D levels were similar for those with and without asthma. The odds of having an exacerbation were 25% greater for those with vitamin D deficiency than for those with vitamin D levels in the normal range. This significant correlation persisted even after adjustment for confounding variables.

“The presented evidence supports vitamin D screening in the subgroup of asthmatics that are uncontrolled and experience recurrent exacerbations,” the authors write.

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