(HealthDay News) –The prevalence of total knee replacement is estimated at 4.2% for U.S. adults aged ≥50 years, according to a study published in the March 6 issue of The Journal of Bone & Joint Surgery.

Alexander M. Weinstein, of the Brigham and Women’s Hospital in Boston, and colleagues utilized the Osteoarthritis Policy Model, combined with data on utilization of total knee replacement, to estimate the prevalence and lifetime risks of primary and revision total knee replacement among adults in the United States.

The researchers estimated that the number of U.S. adults currently living with a total knee replacement was 4 million, representing an overall prevalence of 4.2% among adults ≥50 years of age. The prevalence of total knee replacement increased with age and was higher among females (4.8%) than males (3.4%). For females and males, the lifetime risk of primary total knee replacement from the age of 25 years was 9.5% and 7%, respectively. More than half of U.S. adults diagnosed with knee osteoarthritis will undergo total knee replacement.

“While total knee replacement is a remarkably successful treatment for individuals with end-stage knee osteoarthritis, our findings emphasize the large public health burden posed by the millions of adults in the United States living with total knee replacement,” the authors write.

One or more authors disclosed financial ties to an entity in the biomedical arena.

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