Objective: To assess the current literature on the impact of rheumatoid arthritis (RA) treatments on the humoral response to pneumococcal and influenza vaccines. Influenza vaccination response was reduced for RTX (43 patients; pooled odds ratio [OR] 0.44 [95% confidence interval (95% CI) 0.17 1.12] for H1N1, OR 0.11 [95% CI 0.04 0.31] for H3N2, and OR 0.29 [95% CI 0.10 0.81] for B) but not for anti-TNF.

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