(HealthDay News) – For patients within two years of stent placement, factors associated with major cardiac adverse events after non-cardiac operations have been identified, according to a study published online Oct. 7 in the Journal of the American Medical Association to coincide with presentation at the annual meeting of the American College of Surgeons, held from Oct. 6–10 in Washington, DC.

Mary T. Hawn, MD, MPH, from the Birmingham Veterans Administration Hospital in Alabama, and colleagues conducted a national, retrospective cohort study to examine the risk factors for major adverse cardiac events (MACE) in non-cardiac surgery.

Within 24 months of 124,844 coronary stent implantations, the researchers identified 1,980 MACE in 28,029 patients who underwent non-cardiac operations. There was a significant correlation between the time between stent and surgery and MACE. The factors most strongly linked to MACE were non-elective surgical admission (adjusted odds ratio [aOR], 4.77); history of myocardial infarction in the six months before surgery (aOR, 2.63); and revised cardiac risk index >2 (aOR, 2.13). The risk of MACE was stable at six months after stent placement.

“Among patients undergoing non-cardiac surgery within two years of coronary stent placement, MACE were associated with emergency surgery and advanced cardiac disease but not stent type or timing of surgery beyond six months after stent implantation,” the authors write.

One author disclosed financial ties to the pharmaceutical industry.

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