(HealthDay News) – In women with pelvic organ prolapse who undergo abdominal sacrocolpopexy, the failure rates increase with longer follow-up, according to a study published in the May 15 issue of the Journal of the American Medical Association.

Ingrid Nygaard, MD, from the University of Utah School of Medicine in Salt Lake City, and colleagues analyzed anatomic and symptomatic outcomes for 215 women with stress continence who underwent abdominal sacrocolpopexy for symptomatic pelvic organ prolapse and were enrolled in extended follow-up studies. The women were part of a clinical trial where 104 had undergone abdominal sacrocolpopexy plus Burch urethropexy and 111 had undergone abdominal sacrocolpopexy alone.

During a median follow-up of seven years, the researchers found that the rates of pelvic organ prolapse and urinary incontinence failure gradually increased in both groups. There was a 10.5% probability of mesh erosion at seven years. The addition of urethropexy prevented stress urinary incontinence longer.

“During seven years of follow-up, abdominal sacrocolpopexy failure rates increased in both groups,” Nygaard and colleagues conclude. “Abdominal sacrocolpopexy effectiveness should be balanced with long-term risks of mesh or suture erosion.”

Several authors disclosed financial ties to pharmaceutical and medical device companies.

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