(HealthDay News) — For adults with diabetes, inadequately controlled risk factors account for a considerable proportion of cardiovascular events and death, according to a study published online in Diabetes Care.
Gabriela Vazquez-Benitez, PhD, from the HealthPartners Institute for Education and Research in Minneapolis, Minn., and colleagues examined the incidence of major cardiovascular hospitalization events and all-cause death among 859,617 adults with diabetes and with or without cardiovascular disease (CVD; 31% had CVD). The authors assessed the correlation between inadequately controlled risk factors (glycated hemoglobin, high low-density lipoprotein cholesterol, high blood pressure, current smoking) and the incidence of major cardiovascular events.
The researchers found that per 100 person-years, event rates for adults with diabetes with CVD vs. without CVD were 6.0 vs. 1.7 for myocardial infarction/acute coronary syndrome, 5.3 vs. 1.5 for stroke, 8.4 vs. 1.2 for heart failure, 18.1 vs. 4.0 for all cardiovascular events, and 23.5 vs. 5.0 for all-cause mortality. Inadequate risk factor control was associated with 11 and 3% of cardiovascular events and deaths, respectively, among those with CVD, and with 34 and 7%, respectively, among those without CVD.
“Additional attention to traditional cardiovascular risk factors could yield further substantive reductions in cardiovascular events and mortality in adults with diabetes,” the authors write.