(HealthDay News) – Middle-aged adults who participate in moderate weekly physical activity do not increase their risk of knee osteoarthritis, according to a study published online Aug. 27 in Arthritis Care & Research.

Kamil Barbour, PhD, from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues utilized data from the Johnston County Osteoarthritis Project study’s first (1999–2004) and second follow-up (2005–2010) to evaluate the association between meeting physical activity guidelines and incident knee outcomes among 1,522 adults aged ≥45 years. The Minnesota Leisure Time Physical Activity questionnaire was used to evaluate baseline physical activity. The development of a Kellgren-Lawrence grade of ≥2 at follow-up defined incident knee OA.

The researchers found that meeting the 2008 U.S. Department of Health and Human Services (HHS) physical activity guidelines (≥150min/wk) was not significantly associated with radiographic OA (ROA; hazard ratio [HR], 1.20; 95% confidence interval [CI], 0.94–1.56) or symptomatic ROA (sROA; HR, 1.24; 95% CI, 0.87–1.76). Compared to inactive participants (0–<10 min/wk), adults in the highest (≥300 min/wk) level of physical activity had a higher risk of knee ROA and sROA (HR, 1.62 [95% CI, 0.97–2.68] and 1.42 [95% CI, 0.76–2.65], respectively).

“Meeting HHS physical activity guidelines was not associated with incident knee ROA or sROA in a cohort of middle-aged and older adults,” the authors write.

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