(HealthDay News) – Older adults who live alone have a higher risk of death; and elderly adults who report loneliness experience increased functional decline and an increased risk of death.

Jacob A. Udell, MD, MPH, from Harvard Medical School in Boston, and colleagues analyzed cardiovascular risk using data from an international registry of 44,573 individuals aged >45 years, of whom 8,594 (19%) lived alone. They found that living alone correlated with significantly higher four-year mortality (14.1 vs. 11.1%) and cardiovascular death (8.6 vs. 6.8%). Age was a significant factor, with younger individuals having higher mortality and a higher risk of cardiovascular death.

Carla M. Perissinotto, MD, MHS, from the University of California in San Francisco, and colleagues analyzed loneliness and quality of life among 1,604 individuals >60 years in the United States, of whom 18% lived alone. They found that, over six years, loneliness was associated with a higher risk of death (22.8 vs. 14.2%) as well as a greater likelihood of declines in activities of daily living, difficulty with upper extremity tasks, decline in mobility, and difficulty in climbing.

“Loneliness is a negative feeling that would be worth addressing even if the condition had no health implications,” write the authors of an accompanying editorial. “With regard to health implications, scientists examining social support should build on studies such as those published in this issue and be challenged to investigate mechanisms as well as practical interventions that can be used to address the social factors that undermine health.”

The pharmaceutical industry funded the registry used in the Udell study; several authors disclosed financial ties to the pharmaceutical industry. An editorial author disclosed ties to UnitedHealth and Medtronic.

Abstract – Udell
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Abstract – Perissinotto
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