Ilknur Balta, MD, from the Ministry of Health in Ankara, Turkey, and colleagues examined the correlation between post-adolescent acne and insulin resistance in a population that included 35 patients with post-adolescent acne and 35 healthy controls.
The researchers found that fasting blood glucose, fasting insulin, aspartate aminotransferase, alanine aminotransferase, triglyceride and high-density lipoprotein cholesterol levels, and the homeostasis model assessment of insulin resistance index did not differ significantly for patients with post-adolescent acne and controls. No correlations were seen for these parameters with acne severity.
“This study suggests that insulin resistance may not play a major role in the pathogenesis of post-adolescent acne,” the authors write. “Hormonal changes, genetic susceptibility, stress, the use of cosmetics, drugs, and environmental factors should be considered in the development of post-adolescent acne.”