(HealthDay News) — Sleep-disordered breathing (SDB) may be associated with adverse pregnancy outcomes, according to research published in the June issue of the American Journal of Obstetrics & Gynecology.

Francesca L. Facco, MD, of the University of Pittsburgh, and colleagues conducted a planned analysis of a prospective cohort of 188 women to assess the prevalence and trends of SDB and its effect on pregnancy outcomes.

The researchers found a dose-dependent relationship between the severity of SDB in early pregnancy and the risk of developing gestational diabetes (no SDB, 25%; mild SDB, 43%; moderate/severe SDB, 63%). Among women with moderate/severe SDB in early pregnancy, the adjusted odds ratio for developing gestational diabetes was 3.6 (95% confidence interval, 0.6–21.8). No association was detected between SDB exposure in early or late pregnancy and any of the other adverse pregnancy outcomes, including preeclampsia, preterm birth <34 weeks, and small-for-gestational-age (less than 5%) or large-for-gestational-age (greater than 95%) neonates.

“This study suggests a dose-dependent relationship between SDB exposure in early pregnancy and the subsequent development of gestational diabetes,” the authors write.

Full Text