(HealthDay News) — Polymethylmethacrylate (PMMA) microspheres in collagen are safe and effective for the treatment of atrophic acne scars of the face, according to a study published in the July issue of the Journal of the American Academy of Dermatology.

Jwala Karnik, MD, from Suneva Medical Inc. in Santa Barbara, CA, and colleagues evaluated PMMA microspheres in collagen (ArteFill) for the treatment of acne scarring. Patients (n=147) with at least four moderate to severe rolling, atrophic scars were randomized to receive either saline or PMMA-collagen injections (up to two injection sessions) and were followed for six months.

The researchers found that success was achieved in 64% of those in the PMMA-collagen group and in 33% of the control group (P=0.0005). PMMA-collagen appeared to have excellent safety with generally mild, reversible adverse events. There were no significant differences in efficacy or safety between genders, for darker skin types, or in older age groups.

“PMMA-collagen demonstrates substantial effectiveness in the treatment of atrophic acne scars of the face while maintaining an excellent safety profile,” the authors write.

The study was funded by Suneva Medical.

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