(HealthDay News) — Fruit and vegetable intake is associated with hip fracture, with a higher rate of hip fracture for intake below five servings/day, according to a study published in the June issue of the Journal of Bone and Mineral Research.

Liisa Byberg, PhD, from Uppsala University in Sweden, and colleagues examined the dose-response association between habitual fruit and vegetable intake and hip fracture in a cohort study involving 40,644 men and 34,947 women (age 45–83 years), free from cardiovascular disease and cancer. Participants were followed for a mean of 14.2 years.

The researchers observed 3,644 hip fractures (62% in women) during 1,037,645 person-years. There was a strong nonlinear dose-response association (P<0.001). Compared with those consuming more than five servings/day, men and women with zero consumption had an 88% higher rate of hip fracture (adjusted hazard ratio, 1.88). With higher intake of fruit and vegetables, the rate was gradually lower (adjusted hazard ratio, 1.35 for one vs. five servings/day). The hazard ratio was no lower for more than five servings/day (adjusted hazard ratio for eight vs. five servings/day, 0.96; 95% confidence interval, 0.90–1.03). The results were similar when men and women were analyzed separately.

“There is a dose-response association between fruit and vegetable intake and hip fracture such that an intake below the recommended five servings/day confers higher rates of hip fracture,” the authors write.

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