(HealthDay News) – From 2000–2010, in the United States, the number of donor oocyte cycles increased, and the number of good perinatal outcomes also increased, according to research published online on Oct. 17 in the Journal of the American Medical Association. This research was published to coincide with presentation at the annual meeting of the American Society for Reproductive Medicine, held from Oct. 12–17 in Boston.

Jennifer F. Kawwass, MD, of Emory University in Atlanta, and colleagues analyzed surveillance data to assess trends in donor oocyte cycles and to identify predictors of good perinatal outcome for in vitro fertilization.

The researchers found that the annual number of donor oocyte cycles increased significantly. Increases were observed in the proportions of donor oocyte cycles using frozen, rather than fresh, embryos, and the elective transfer of single, rather than multiple, embryos. Good perinatal outcomes increased from 18.5% to 24.4%. Factors associated with good perinatal outcome included transfer of an embryo at day five (adjusted odds ratio, 1.17) and elective single-embryo transfers (adjusted odds ratio, 2.32).

“Further studies are needed to understand the mechanisms underlying the factors associated with less successful outcomes,” the authors write.

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