(HealthDay News) — For patients with schizophrenia, community-based care plus facility-based care is associated with a reduction in symptoms and disability over 12 months, according to a study published online March 5 in The Lancet.

Sudipto Chatterjee, MD, from Sangath in Goa, India, and colleagues compared the effectiveness of a collaborative community-based care intervention with standard facility-based care in a trial conducted at three sites in India. Participants were aged 16–60 years with a primary diagnosis of schizophrenia, and were randomized to receive collaborative community-based care plus facility-based care (187 patients) or facility-based care alone (95 patients). Ninety percent of participants completed follow-up at one year.

The researchers found that the total positive and negative syndrome scale (PANSS) and Indian disability evaluation and assessment scale (IDEAS) scores were significantly lower in the intervention group than the control group at 12 months (PANSS mean difference, −3.75; P=0.08; IDEAS mean difference, −0.95; P=0.01). No significant difference was seen in the proportion of patients with >20% reduction in overall symptoms. At the rural Tamil Nadu site, significant reductions were seen in symptom and disability outcomes.

“The collaborative community-based care plus facility-based care intervention is modestly more effective than facility-based care, especially for reducing disability and symptoms of psychosis,” the authors write.

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