Critical Therapeutics has decided to discontinue the manufacturing of Zyflo (zileuton) immediate-release tablets due to a decline in use. Zyflo will remain available through pharmacies and wholesalers until current supplies are depleted which is expected to be around March 1, 2008.Zyflo CR (zileuton extended-release tablets) will continue to be available and healthcare providers are encouraged to convert Zyflo treated patients to Zyflo CR as soon as possible to prevent any disruption in their zileuton therapy.

Zyflo CR is indicated for the prophylaxis and chronic treatment of asthma in patients ≥12 years of age.

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