HealthDay News — The COVID-19 vaccination program in the US prevented a substantial burden of morbidity and mortality, according to a study published online July 6 in JAMA Network Open.

Molly K. Steele, PhD, MPH, from the US Centers for Disease Control and Prevention in Atlanta, and colleagues conducted a modeling study to estimate the number of SARS-CoV-22 infections and COVID-19-associated hospitalizations stratified by state, month, and age group from December 1, 2020, to September 30, 2021, in the US. To estimate the risks for infections, hospitalizations, and deaths, these estimates were combined with data on vaccine coverage and effectiveness.

The researchers found that from December 1, 2020, to September 30, 2021, COVID-19 vaccination prevented an estimated 27 million infections, 1.6 million hospitalizations, and 235,000 deaths among vaccinated adults aged 18 years or older in the US. Vaccination was estimated to have prevented 52, 56, and 58% of expected infections, expected hospitalizations, and expected deaths, respectively, among adults aged 18 years or older from September 1 to September 30, 2021.

“Vaccination is an effective public health intervention with demonstrable impact, which will be critical in combination with nonpharmaceutical interventions to mitigate the COVID-19 pandemic,” the authors write.

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