HealthDay News — The burden of chronic kidney disease (CKD) increased in the United States between 2002 and 2016, although there was variability by state, according to a study published online November 30 in JAMA Network Open.

Benjamin Bowe, MPH, from the Veterans Affairs St. Louis Health Care System, and colleagues assessed changes in the burden of CKD at the state level from 2002 to 2016. The authors analyzed data and methodologies from the 2016 Global Burden of Disease study in the United States.

The researchers found that during the study period, CKD disability-adjusted life years (DALYs) increased by 52.6%. Death due to CKD increased by 58.3%, from 52,127 to 82,539 deaths. All states experienced increases in CKD burden; however, there was variance by state in the rate of change and the 2016 burden. The burden was twice as high in states in the southern United States (including Mississippi and Louisiana). Increased risk exposure (40.3%), aging (32.3%), and population growth (27.4%) contributed to the increase in CKD DALYs. Adjusting for age, CKD DALY rates increased by 18.6%, with increases in metabolic and dietary risk factors contributing to 93.8 and 5.3 percent of this change, respectively. Among those aged 55 to 89 years, the probability of death due to CKD increased by 25.6 percent and was driven by diabetes-related CKD. 

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“The findings suggest the need to target chronic kidney disease burden by addressing risk exposure among young adults,” the authors write.

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